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  • HIV-1: What It Is and What You Need to Know

    2017-3-19 · HIV-1一种能攻击人体内脏系统的病毒。. 它把 人体免疫系统 中最重要的T4淋巴组织作为攻击目标,大量破坏T4淋巴组织,产生高致命性的内衰竭。. 这种病毒在地域内终生传染,破坏人的免疫平衡,使人体成为各种疾病的载体。. HIV-1身并不会引发任何疾病,而是当免疫系统被HIV破坏后,人体由于抵抗能力过低,丧失复制免疫细胞的机会,从而感染其他的疾病导致各种 ...

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  • HIV-1 subtypes | aidsmap

    2014-4-9 · 中国HIV-1基因亚型分布及流行趋势 Distribution of HIV-1 genotypes in China:a systematic review 收稿日期:2014-04-09 出版日期:2014-09-15 DOI: 10.3760/cma.j.issn.0254-6450.2014.10.020 中文关键词: 人类免疫缺陷病毒-1;基因型;系统综述 英文关键词: HIV-1

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  • HIV-1 | definition of HIV-1 by Medical dictionary

    HIV-1: AIDS-related virus–ARV, Human immunodeficiency virus, human T-cell lymphotrophic virus, type III–HTLV-III, lymphadenopathy-associated virus–LAV The retrovirus intimately linked to AIDS Skin in HIV See HIV dermatopathy Diagnosis PCR, ELISA to screen for anti-HIV IgM antibodies; ELISA-positive sera is subjected to Western immunoblot ...

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  • HIV/AIDS - WHO

    2018-7-10 · 据WHO统计,截至2015年全球HIV-1感染者约3600万,每年新增感染者超过200万,而获得抗逆转录病毒治疗(ART)的患者只有1820万。

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  • HIV-1 Interactions Database - National Institutes of

    2014-7-25 · Search criteria Interaction type Protein Replication Both Gene Ontology (GO) Protein domain name Properties Has phenotype Has gene expression data Has Homologene Cluster Has >1 …

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  • HIV-1 reverse transcription - PubMed

    Reverse transcription and integration are the defining features of the Retroviridae; the common name 'retrovirus' derives from the fact that these viruses use a virally encoded enzyme, reverse transcriptase (RT), to convert their RNA genomes into DNA. Reverse transcription is an essential step in re …

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  • HIV-1 vs. HIV-2: Differences and similarities

    2018-12-8 · 对HIV-1进行持续的分子流行病学监测对于HIV-1疫苗的开发以及保持HIV-1诊断和病毒载量检测的准确性仍然至关重要。” 在全球范围内,在2010年至2015年,HIV-1亚型C占所有HIV-1感染的将近一半(46.6%)。 HIV-1亚型B导致12.1%的感染,HIV-1亚型A导致10

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  • PSGL-1 restricts HIV-1 infectivity by blocking virus ...

    人类免疫缺陷病毒1型 (HIV-1)核酸测定试剂盒 (PCR-荧光探针法) 核酸提取试剂(适用于大包装规格、单管单人份规格):离心柱、收集管、病毒裂解液、抑制物去除液(浓缩液)、去离子液(浓缩液)、洗脱液、蛋白酶K(干粉)、CarrierRNA(干粉);质控品及阳性 ...

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  • HIV-1 subtypes | aidsmap

    2015-6-29 · HIV-1 is the causative agent of AIDS, one of the most devastating viral pandemics in history. Although effective treatments are available to suppress HIV-1 replication in infected patients ...

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  • HIV-1 assembly, release and maturation | Nature

    HIV-1 protease (HIV-1 PR) is a dimeric enzyme from the family of aspartic proteases. The enzyme has been widely exploited as a drug target and exhibits broad substrate recognition. HIV-1 protease can be detected through designed interactions with multiple peptide sensors (Fig. 7.8; Herpoldt et al., 2015).An energy transfer can happen between two peptide sensors with simultaneous mixing with ...

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  • HIV-1 Protease - an overview | ScienceDirect Topics

    提供全面的“HIV-1蛋白酶”相关文献(论文)下载,论文摘要免费查询,HIV-1蛋白酶论文全文下载提供PDF格式文件。HIV-1蛋白酶中文、英文词汇释义(解释),“HIV-1蛋白酶”各类研究资料、调研报告等。

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  • HIV strains and types | Avert

    2016-12-7 · 最好像这个图一样

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  • HIV Types and Strains - WebMD

    2021-6-30 · There are two main types of human immunodeficiency virus (HIV) -- HIV-1 and HIV-2.Both can lead to AIDS. However, they're very different from each other. HIV-1 is the most common type.

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  • The structural biology of HIV-1: mechanistic and ...

    2012-3-16 · HIV-1 replication relies on the proper functioning of specific viral proteins, three of which — protease, integrase, and reverse transcriptase with associated RNase H activity — are enzymes.

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  • Multi-omics analyses reveal that HIV-1 alters CD4 + T

    2021-3-25 · HIV-1 viral load set point in patients positively correlates with oxidative phosphorylation. Immunometabolism is dysregulated in patients with HIV-1 and is associated with HIV-1 cellular ...

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  • HIV-1 vs. HIV-2: Differences and similarities

    2019-1-1 · 由于HIV-1逆转录发生在细胞质中,因此检测了没有NLS的Cas9(Cas9-delNLS)不位于细胞核内,是否也能够裂解细胞质中新合成的HIV-1 DNA,从而抑制HIV-1感染。 注:NLS,核定位序列(Nuclear localization sequence)——蛋白质的一个结构域,通常为一短的氨基酸序列,它能与入核载体相互作用,使蛋白能被运进细胞核。

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  • HIV-1 versus HIV-2: What’s the Difference? - Medical

    2017-11-22 · HIV-1的病毒核心蛋白具有较好的免疫原性,是HIV最保守的蛋白之一。 env基因编码病毒包膜蛋白, gp160是HIV包膜糖蛋白前体。 该前体蛋白在蛋白酶的作用下被切割成外膜蛋白gp120和跨膜蛋 …

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  • CARD8 is an inflammasome sensor for HIV-1 protease ...

    2016-3-23 · Elimination of HIV-1 Genomes from Human T-lymphoid Cells by CRISPR/Cas9 Gene Editing doi:10.1038/srep22555 Rafal Kaminski, Yilan Chen, Tracy Fischer, Ellen Tedaldi, Alessandro Napoli, Yonggang Zhang, Jonathan Karn, Wenhui Hu & Kamel Khalili

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